E-ISSN 1858-8360 | ISSN 0256-4408
 

Original Article 


Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia

Nada A. Alharbi, Thamir S. Alsaeed, Arwa S. Aljohany, Khulood K. Alwehaibi, Munira A. Almasaad, Rawan M. Alotaibi, Basil J. Alotaibi, Ebtihal A. Alamoudi.

Abstract
Introduction: Salmonella infection is one of the most common causes of gastroenteritis worldwide. It is associated with high morbidity and mortality if not treated properly. It has developed resistance to multiple antibiotics. These developments are concerning. This study sought to observe common patterns of invasive Salmonella infections, such as the common serotypes involved, presentation, sensitive investigations, and effective treatment. This study also aimed to examine the risk factors that can worsen the infection and increase morbidity and mortality.
Methodology: This retrospective analysis included all patients who were diagnosed with invasive Salmonella infection at King Khalid University Hospital from May 2017 to December 2018. Most patients in this report were immunocompromised; however, a few previously healthy patients. Different types of specimens were collected. Twenty-two patients with invasive Salmonella were included in this study.
Results: Sixteen of them had underlying conditions. The most common presenting symptoms of illness were fever (n = 13), vomiting (n = 6), and diarrhea (n = 4). Most blood samples (94%) were positive for Salmonella. All patients were discharged except three who died; these were all older patients with comorbidities. Although four different antimicrobial resistance patterns were noticed in this study, ciprofloxacin
was the highest significant percentage (62.5%). Of five patients initially treated with ciprofloxacin, three of them expressed resistance to this antibiotic.
Conclusion: The findings of this study support that immunocompromised patients and people with extreme ages are more likely to have serious medical illnesses and at higher risk of infection with Salmonella spp. Therefore, this study emphasises the importance of antimicrobial judicious utilisation. Tackling the escalating antibiotic resistance could be approached by implementing advanced public education levels to maintain high standards of food and water safety. Moreover, the urge to investigating newer drugs against Salmonella with an acceptable safety profile is a cornerstone to attenuate the rapidly acquired bacterial resistance precisely for those who are immunocompromised. Furthermore, predicting the mortality, morbidity and the clinical response is feasible according to the patient parameters and comorbidities.

Key words: Immunocompromised; invasive; ciprofloxacin resistance; Salmonella; Saudi Arabia.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Nada A. Alharbi
Articles by Thamir S. Alsaeed
Articles by Arwa S. Aljohany
Articles by Khulood K. Alwehaibi
Articles by Munira A. Almasaad
Articles by Rawan M. Alotaibi
Articles by Basil J. Alotaibi
Articles by Ebtihal A. Alamoudi
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Alharbi NA, Alsaeed TS, Aljohany AS, Alwehaibi KK, Almasaad MA, Alotaibi RM, Alotaibi BJ, Alamoudi EA. Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia. Sudan J Paed. 2021; 21(2): 152-161. doi:10.24911/SJP.106-1594309379


Web Style

Alharbi NA, Alsaeed TS, Aljohany AS, Alwehaibi KK, Almasaad MA, Alotaibi RM, Alotaibi BJ, Alamoudi EA. Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia. https://www.sudanjp.com/?mno=95726 [Access: August 03, 2022]. doi:10.24911/SJP.106-1594309379


AMA (American Medical Association) Style

Alharbi NA, Alsaeed TS, Aljohany AS, Alwehaibi KK, Almasaad MA, Alotaibi RM, Alotaibi BJ, Alamoudi EA. Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia. Sudan J Paed. 2021; 21(2): 152-161. doi:10.24911/SJP.106-1594309379



Vancouver/ICMJE Style

Alharbi NA, Alsaeed TS, Aljohany AS, Alwehaibi KK, Almasaad MA, Alotaibi RM, Alotaibi BJ, Alamoudi EA. Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia. Sudan J Paed. (2021), [cited August 03, 2022]; 21(2): 152-161. doi:10.24911/SJP.106-1594309379



Harvard Style

Alharbi, N. A., Alsaeed, . T. S., Aljohany, . A. S., Alwehaibi, . K. K., Almasaad, . M. A., Alotaibi, . R. M., Alotaibi, . B. J. & Alamoudi, . E. A. (2021) Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia. Sudan J Paed, 21 (2), 152-161. doi:10.24911/SJP.106-1594309379



Turabian Style

Alharbi, Nada A., Thamir S. Alsaeed, Arwa S. Aljohany, Khulood K. Alwehaibi, Munira A. Almasaad, Rawan M. Alotaibi, Basil J. Alotaibi, and Ebtihal A. Alamoudi. 2021. Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia. Sudanese Journal of Paediatrics, 21 (2), 152-161. doi:10.24911/SJP.106-1594309379



Chicago Style

Alharbi, Nada A., Thamir S. Alsaeed, Arwa S. Aljohany, Khulood K. Alwehaibi, Munira A. Almasaad, Rawan M. Alotaibi, Basil J. Alotaibi, and Ebtihal A. Alamoudi. "Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia." Sudanese Journal of Paediatrics 21 (2021), 152-161. doi:10.24911/SJP.106-1594309379



MLA (The Modern Language Association) Style

Alharbi, Nada A., Thamir S. Alsaeed, Arwa S. Aljohany, Khulood K. Alwehaibi, Munira A. Almasaad, Rawan M. Alotaibi, Basil J. Alotaibi, and Ebtihal A. Alamoudi. "Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia." Sudanese Journal of Paediatrics 21.2 (2021), 152-161. Print. doi:10.24911/SJP.106-1594309379



APA (American Psychological Association) Style

Alharbi, N. A., Alsaeed, . T. S., Aljohany, . A. S., Alwehaibi, . K. K., Almasaad, . M. A., Alotaibi, . R. M., Alotaibi, . B. J. & Alamoudi, . E. A. (2021) Extra-intestinal Salmonellosis in a Tertiary Care Center in Saudi Arabia. Sudanese Journal of Paediatrics, 21 (2), 152-161. doi:10.24911/SJP.106-1594309379





Most Viewed Articles
  • Rheumatic heart disease in North Darfur: an alarmingly high burden and control initiative
    Nagwa Salih, Ishag Eisa, Daresalam Ishag, Intisar Ibrahim, Sulafa Ali
    Sudan J Paed. 2018; 18(1): 24-27
    » Abstract » doi: 10.24911/SJP.2018.1.4

  • Feeding growth restricted premature neonates: a challenging perspective
    Siba Prosad Paul, Emily Natasha Kirkham, Katherine Amy Hawton, Paul Anthony Mannix
    Sudan J Paed. 2018; 18(2): 5-14
    » Abstract » doi: 10.24911/SJP.106-1519511375

  • Congenital brain malformations in Sudanese children: an outpatient-based study
    Inaam Noureldyme Mohammed, Soad Abdalaziz Suliman, Maha A Elseed, Ahlam Abdalrhman Hamed, Mohamed Osman Babiker, Shaimaa Osman Taha
    Sudan J Paed. 2018; 18(1): 48-56
    » Abstract » doi: 10.24911/SJP.2018.1.7

  • Evaluation of Science. [eng]
    Adnan Mahmmood Usmani; Sultan Ayoub Meo
    Sudan J Paed. 2011; 11(1): 6-7
    » Abstract

  • Medical education and services in an extreme environment
    Mustafa Abdalla M. Salih, Mohammed Osman Swar
    Sudan J Paed. 2018; 18(1): 2-5
    » Abstract » doi: 10.24911/SJP.2018.1.1

  • Most Downloaded
  • The role of micronutrients in thyroid dysfunction
    Amir Babiker, Afnan Alawi, Mohsen Al Atawi, Ibrahim Al Alwan
    Sudan J Paed. 2020; 20(1): 13-19
    » Abstract » doi: 10.24911/SJP.106-1587138942

  • Why mothers are not exclusively breast feeding their babies till 6 months of age? Knowledge and practices data from two large cities of the Kingdom of Saudi Arabia
    Hafsa Raheel, Shabana Tharkar
    Sudan J Paed. 2018; 18(1): 28-38
    » Abstract » doi: 10.24911/SJP.2018.1.5

  • Inborn errors of metabolism associated with hyperglycaemic ketoacidosis and diabetes mellitus: narrative review
    Majid Alfadhel, Amir Babiker
    Sudan J Paed. 2018; 18(1): 10-23
    » Abstract » doi: 10.24911/SJP.2018.1.3

  • Relactation in lactation failure and low milk supply
    Anita Mehta, Arvind Kumar Rathi, Komal Prasad Kushwaha, Abhishek Singh
    Sudan J Paed. 2018; 18(1): 39-47
    » Abstract » doi: 10.24911/SJP.2018.1.6

  • Severe desquamation in Kawasaki disease: Is it somehow protective?
    Jubran Theeb Alqanatish, Amir Babiker
    Sudan J Paed. 2017; 17(2): 56-59
    » Abstract » doi: 10.24911/SJP.2017.2.7

  • Most Cited Articles
  • Anti-diabetic medications: How to make a choice?
    Amir Babiker, Mohammed Al Dubayee
    Sudan J Paed. 2017; 17(2): 11-20
    » Abstract » doi: 10.24911/SJP.2017.2.12
    Cited : 8 times [Click to see citing articles]

  • Broad beans ( Vicia faba ) and the potential to protect from COVID-19 coronavirus infection
    Mutasim I. Khalil, Mustafa A. Salih, Ali A. Mustafa
    Sudan J Paed. 2020; 20(1): 10-12
    » Abstract » doi: 10.24911/SJP.1061585398078
    Cited : 4 times [Click to see citing articles]

  • Challenges in the diagnosis and management of Pediatric Rheumatology in the developing world: Lessons from a newly established clinic in Yemen
    Haifa Ali Bin Dahman
    Sudan J Paed. 2017; 17(2): 21-29
    » Abstract » doi: 10.24911/SJP.2017.2.2
    Cited : 4 times [Click to see citing articles]

  • Pattern of malaria in hospitalized children in Khartoum state
    Hasan Awadalla Hashim, Eltigani Mohamed Ahmed Ali
    Sudan J Paed. 2017; 17(2): 35-41
    » Abstract » doi: 10.24911/SJP.2017.2.4
    Cited : 4 times [Click to see citing articles]

  • Commitment to the wellbeing of children worldwide. [eng]
    Mustafa Abdalla M Salih; Satti Abdelrahim Satti
    Sudan J Paed. 2011; 11(2): 4-5
    » Abstract
    Cited : 4 times [Click to see citing articles]