E-ISSN 1858-8360 | ISSN 0256-4408
 

Case Report 


Vitamin K deficiency bleeding of newborn masquerading haemophilia B

Mritunjay Kumar, Sidharth Kumar, Shivani Bajpayi, Rashmi Kumari.

Abstract
The term infant is remarkably resistant to bleeding despite physiologically low levels of procoagulant proteins. However, because of their unique haemostatic systems, neonates are vulnerable to haemorrhagic disorders. The prevention of early vitamin K deficiency bleeding (VKDB) of newborn by oral or parenteral administration of vitamin K has been well established. However, rarely, a newborn can present with bleeding manifestations even after routine vitamin K prophylaxis at birth. A 2-day-old healthy male baby presented with catastrophic pulmonary haemorrhage with severely deranged coagulation profile even after receiving vitamin K prophylaxis at birth. His presentation, initial laboratory findings and course in the hospital were very much in favour of haemophilia B, but follow-up factor IX level and clinical exome sequencing did not confirm it. However, protein induced in vitamin K absence-II was found to be raised just before the discharge, and we concluded this case as a rare presentation of classical VKDB.

Key words: Newborn; Bleeding; Vitamin K deficiency bleeding (VKDB); Protein induced in vitamin K absence-II (PIVKA-II); Haemophilia.


 
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How to Cite this Article
Pubmed Style

Kumar M, Kumar S, Bajpayi S, Kumari R. Vitamin K deficiency bleeding of newborn masquerading haemophilia B. Sudan J Paed. 2020; 20(2): 176-180. doi:10.24911/SJP.106-1584209747


Web Style

Kumar M, Kumar S, Bajpayi S, Kumari R. Vitamin K deficiency bleeding of newborn masquerading haemophilia B. http://www.sudanjp.com/?mno=92551 [Access: August 13, 2020]. doi:10.24911/SJP.106-1584209747


AMA (American Medical Association) Style

Kumar M, Kumar S, Bajpayi S, Kumari R. Vitamin K deficiency bleeding of newborn masquerading haemophilia B. Sudan J Paed. 2020; 20(2): 176-180. doi:10.24911/SJP.106-1584209747



Vancouver/ICMJE Style

Kumar M, Kumar S, Bajpayi S, Kumari R. Vitamin K deficiency bleeding of newborn masquerading haemophilia B. Sudan J Paed. (2020), [cited August 13, 2020]; 20(2): 176-180. doi:10.24911/SJP.106-1584209747



Harvard Style

Kumar, M., Kumar, . S., Bajpayi, . S. & Kumari, . R. (2020) Vitamin K deficiency bleeding of newborn masquerading haemophilia B. Sudan J Paed, 20 (2), 176-180. doi:10.24911/SJP.106-1584209747



Turabian Style

Kumar, Mritunjay, Sidharth Kumar, Shivani Bajpayi, and Rashmi Kumari. 2020. Vitamin K deficiency bleeding of newborn masquerading haemophilia B. Sudanese Journal of Paediatrics, 20 (2), 176-180. doi:10.24911/SJP.106-1584209747



Chicago Style

Kumar, Mritunjay, Sidharth Kumar, Shivani Bajpayi, and Rashmi Kumari. "Vitamin K deficiency bleeding of newborn masquerading haemophilia B." Sudanese Journal of Paediatrics 20 (2020), 176-180. doi:10.24911/SJP.106-1584209747



MLA (The Modern Language Association) Style

Kumar, Mritunjay, Sidharth Kumar, Shivani Bajpayi, and Rashmi Kumari. "Vitamin K deficiency bleeding of newborn masquerading haemophilia B." Sudanese Journal of Paediatrics 20.2 (2020), 176-180. Print. doi:10.24911/SJP.106-1584209747



APA (American Psychological Association) Style

Kumar, M., Kumar, . S., Bajpayi, . S. & Kumari, . R. (2020) Vitamin K deficiency bleeding of newborn masquerading haemophilia B. Sudanese Journal of Paediatrics, 20 (2), 176-180. doi:10.24911/SJP.106-1584209747





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