E-ISSN 1858-8360 | ISSN 0256-4408
 

Original Research (Original Article) 


Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed.

Abstract
Seizures in children and neonatal period have variety of causes; however, most of childhood seizures are idiopathic. The aim of this study was to review the causes of epilepsy in children presenting in the first 2 years of life using the International League Against Epilepsy classification released in 2010. This was a retrospective chart review study that was conducted at a tertiary center in Saudi Arabia. Two hundred and twenty-one patients were included in the study, 31 with conditions mimic epilepsy were excluded. The remaining 190 patients were classified into: Group A, structural/metabolic, 82 (43%); Group B, genetic, 24 (13%) and Group C, unknown, 84 (44%). The commonest seizures’ type was tonic–clonic in 106 (56%), followed by clonic 29 (15.3%), myoclonic 22 (11.6%) and a tonic 16 (8.4%). Pyramidal signs, global developmental delay, hypotonia, micro/macrocephaly and abnormal computed tomography and/or magnetic resonance imaging brain were more common in the structural/metabolic group (p < 0.05). Electroencephalography was abnormal in 136 (72%) patients, mostly in the structural/metabolic group (p = 0.011). In conclusion, the aetiology of epilepsy in this cohort was mainly unknown or secondary to structural/metabolic causes.

Key words: Childhood; Epilepsy; Aetiology; Saudi Arabia; Seizures.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Noufa Alonazi
Articles by Abdulrahman Alnemri
Articles by Ebtessam El Melegy
Articles by Noon Mohamed
Articles by Iman Talaat
Articles by Amany Hosny
Articles by Sarar Mohamed
on Google
on Google Scholar
Article Statistics
 Viewed: 424
Downloaded: 175
Cited: 0

How to Cite this Article
Pubmed Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed. Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia. Sudan J Paed. 2018; 18(1): 57-62. doi:10.24911/SJP.2018.1.8


Web Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed. Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia. http://www.sudanjp.com/?mno=295710 [Access: December 10, 2018]. doi:10.24911/SJP.2018.1.8


AMA (American Medical Association) Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed. Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia. Sudan J Paed. 2018; 18(1): 57-62. doi:10.24911/SJP.2018.1.8



Vancouver/ICMJE Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed. Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia. Sudan J Paed. (2018), [cited December 10, 2018]; 18(1): 57-62. doi:10.24911/SJP.2018.1.8



Harvard Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed (2018) Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia. Sudan J Paed, 18 (1), 57-62. doi:10.24911/SJP.2018.1.8



Turabian Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed. 2018. Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia. Sudanese Journal of Paediatrics, 18 (1), 57-62. doi:10.24911/SJP.2018.1.8



Chicago Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed. "Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia." Sudanese Journal of Paediatrics 18 (2018), 57-62. doi:10.24911/SJP.2018.1.8



MLA (The Modern Language Association) Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed. "Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia." Sudanese Journal of Paediatrics 18.1 (2018), 57-62. Print. doi:10.24911/SJP.2018.1.8



APA (American Psychological Association) Style

Noufa Alonazi, Abdulrahman Alnemri, Ebtessam El Melegy, Noon Mohamed, Iman Talaat, Amany Hosny, Sarar Mohamed (2018) Clinical characteristics and aetiology of early childhood epilepsy: a single centre experience in Saudi Arabia. Sudanese Journal of Paediatrics, 18 (1), 57-62. doi:10.24911/SJP.2018.1.8





Most Viewed Articles
  • Blood tests are not always helpful in predicting bacterial meningitis in children. [eng]
    Taha I Yousif; Katie O'Reilly; Montasser Nadeem
    Sudan J Paed. 2016; 16(2): 77-79
    » Abstract

  • Evaluation of Science. [eng]
    Adnan Mahmmood Usmani; Sultan Ayoub Meo
    Sudan J Paed. 2011; 11(1): 6-7
    » Abstract

  • Commitment to the wellbeing of children worldwide. [eng]
    Mustafa Abdalla M Salih; Satti Abdelrahim Satti
    Sudan J Paed. 2011; 11(2): 4-5
    » Abstract

  • X-linked hypophosphatemic rickets (PHEX mutation): A case report and literature review. [eng]
    Badi Alenazi; M A Maleque Molla; Abdullah Alshaya; Mahmoud Saleh
    Sudan J Paed. 2017; 17(1): 61-65
    » Abstract

  • About the Cover. [eng]

    Sudan J Paed. 2016; 16(2): i-i
    » Abstract

  • The Editors of Sudanese Journal of Paediatrics would like to thank. [eng]

    Sudan J Paed. 2016; 16(2): 99-99
    » Abstract

  • Four decades of the Sudanese Journal of Paediatrics and milstones. [eng]
    Mustafa Abdalla M Salih; Mohammed Osman Swar
    Sudan J Paed. 2017; 17(1): 5-9
    » Abstract

  • The nature and prevalence of psychiatric disorders in a Sudanese juvenile correctional facility. [eng]
    Ayaa Siddig Abdelrahman Ali; Mohamed Ali Awadelkarim
    Sudan J Paed. 2016; 16(2): 28-40
    » Abstract

  • Bartter syndrome associated with nephropathic cystinosis. [eng]
    Nader M Osman; Ali Al Sanosi
    Sudan J Paed. 2016; 16(2): 93-98
    » Abstract

  • A new horizon for the Sudanese Journal of Paediatrics. [eng]
    Mustafa Abdalla M Salih; Satti Abdelrahim Satti
    Sudan J Paed. 2011; 11(1): 4-5
    » Abstract

  • Most Downloaded
  • Inborn errors of metabolism associated with hyperglycaemic ketoacidosis and diabetes mellitus: narrative review
    Majid Alfadhel, Amir Babiker
    Sudan J Paed. 2018; 18(1): 10-23
    » Abstract » doi: 10.24911/SJP.2018.1.3

  • Burosumab - a new drug to treat hypophosphatemic rickets
    Stepan Kutilek, Amir Babiker, Badi Alenazi
    Sudan J Paed. 2017; 17(2): 71-73
    » Abstract » doi: 10.24911/SJP.2017.2.11

  • Article authored by three generations: International lifetime commitment to child health
    Mustafa Abdalla M Salih, Mohammed Osman Swar
    Sudan J Paed. 2017; 17(2): 5-10
    » Abstract » doi: 10.24911/SJP.2017.2.1

  • Why mothers are not exclusively breast feeding their babies till 6 months of age? Knowledge and practices data from two large cities of the Kingdom of Saudi Arabia
    Hafsa Raheel, Shabana Tharkar
    Sudan J Paed. 2018; 18(1): 28-38
    » Abstract » doi: 10.24911/SJP.2018.1.5

  • Ethical considerations about changing parental attitude towards end-of-life care in twins with lethal disease
    Mohamad-Hani Temsah
    Sudan J Paed. 2018; 18(1): 76-82
    » Abstract » doi: 10.24911/SJP.2018.1.11

  • Severe desquamation in Kawasaki disease: Is it somehow protective?
    Jubran Theeb Alqanatish, Amir Babiker
    Sudan J Paed. 2017; 17(2): 56-59
    » Abstract » doi: 10.24911/SJP.2017.2.7

  • Anti-diabetic medications: How to make a choice?
    Amir Babiker, Mohammed Al Dubayee
    Sudan J Paed. 2017; 17(2): 11-20
    » Abstract » doi: 10.24911/SJP.2017.2.12

  • Medical education and services in an extreme environment
    Mustafa Abdalla M. Salih, Mohammed Osman Swar
    Sudan J Paed. 2018; 18(1): 2-5
    » Abstract » doi: 10.24911/SJP.2018.1.1

  • Congenital brain malformations in Sudanese children: an outpatient-based study
    Inaam Noureldyme Mohammed, Soad Abdalaziz Suliman, Maha A Elseed, Ahlam Abdalrhman Hamed, Mohamed Osman Babiker, Shaimaa Osman Taha
    Sudan J Paed. 2018; 18(1): 48-56
    » Abstract » doi: 10.24911/SJP.2018.1.7

  • The relationship between birth weight and congenital heart disease at Ahmed Gasim Cardiac Centre, Bahri, Sudan
    Hafiz Osama Hafiz Elshazali, Osama Hafiz Elshazali, Hafiz Elshazali
    Sudan J Paed. 2017; 17(2): 49-55
    » Abstract » doi: 10.24911/SJP.2017.2.6

  • Most Cited Articles
  • Commitment to the wellbeing of children worldwide. [eng]
    Mustafa Abdalla M Salih; Satti Abdelrahim Satti
    Sudan J Paed. 2011; 11(2): 4-5
    » Abstract
    Cited : 4 times [Click to see citing articles]

  • Evaluation of Science. [eng]
    Adnan Mahmmood Usmani; Sultan Ayoub Meo
    Sudan J Paed. 2011; 11(1): 6-7
    » Abstract
    Cited : 1 time [Click to see citing article]

  • Burosumab - a new drug to treat hypophosphatemic rickets
    Stepan Kutilek, Amir Babiker, Badi Alenazi
    Sudan J Paed. 2017; 17(2): 71-73
    » Abstract » doi: 10.24911/SJP.2017.2.11
    Cited : 1 time [Click to see citing article]