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2025, Vol: 25, Issue: 2
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Original Article
Online Published: 01 Jun 2025
 


Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring

Taha I. Yousif.


Abstract
Gastroesophageal reflux (GOR) is a normal phenomenon that occurs in children and adults after meals, mostly asymptomatic and lasting less than 3 minutes. The prevalence is 50% and 5% at 3 months and one year of age, respectively. Diagnosis is with multi-channel intraluminal impedance pH (MII-pH) study. Our aim is to evaluate the physiological values of MII-pH in children less than 16 years of age. Two groups, infants less than one year old and older children 1-16 years, were studied separately. We also studied group 1-6 years of age to study age effect. We used the MII-pH analysis results of patients with no risk factors for gastroesophageal reflux disease (GORD) who were referred for assessment of GORD during the study period to calculate the mean+/- 2SD deviations (or the median if data is skewed), which we propose to be the near-normal values. Out of 1183 patients, 849 were enrolled. Data distribution was skewed. We found that our population’s values are in general different from the currently used ones. Our data showed that total reflux episodes in children (but not infants), acid exposure time, and percentage of exposure more than 5 minutes are all higher (in infants and children) than the currently used values. We found no age effect between older and young children 1-6 years of age. To our knowledge, this is the largest study to assess normal values of GORD in paediatrics to date. Our study showed that currently used values could over diagnose GORD in children.

Key words: Paediatrics GORD, pH Impedance, gastro-oesophageal reflux, Impedance, pH study, normal values of impedance study in children.


 
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Pubmed Style

Taha I. Yousif. Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring. Sudan J Paed. 2025; 25(1): 48-57. doi:10.24911/SJP.106-1736801636

Web Style

Taha I. Yousif. Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring. https://sudanjp.com//?mno=237542 [Access: June 27, 2026]. doi:10.24911/SJP.106-1736801636

AMA (American Medical Association) Style

Taha I. Yousif. Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring. Sudan J Paed. 2025; 25(1): 48-57. doi:10.24911/SJP.106-1736801636


Vancouver/ICMJE Style

Taha I. Yousif. Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring. Sudan J Paed. (2025), [cited June 27, 2026]; 25(1): 48-57. doi:10.24911/SJP.106-1736801636


Harvard Style

Taha I. Yousif (2025) Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring. Sudan J Paed, 25 (1), 48-57. doi:10.24911/SJP.106-1736801636


Turabian Style

Taha I. Yousif. 2025. Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring. Sudanese Journal of Paediatrics, 25 (1), 48-57. doi:10.24911/SJP.106-1736801636


Chicago Style

Taha I. Yousif. "Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring." Sudanese Journal of Paediatrics 25 (2025), 48-57. doi:10.24911/SJP.106-1736801636


MLA (The Modern Language Association) Style

Taha I. Yousif. "Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring." Sudanese Journal of Paediatrics 25.1 (2025), 48-57. Print. doi:10.24911/SJP.106-1736801636


APA (American Psychological Association) Style

Taha I. Yousif (2025) Assessment of physiological values of gastroesophageal reflux in children by using combined multi-channel intraluminal impedance and pH monitoring. Sudanese Journal of Paediatrics, 25 (1), 48-57. doi:10.24911/SJP.106-1736801636




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