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Case Report 


The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion

Saime Ergen Dibeklioglu, Veysel Nijat Bas, Emine Esin Yalinbas, Sermin Tok Umay.

Abstract
Subcutaneous fat necrosis (SCFN) is an uncommon cause of neonatal hypercalcemia. It is usually seen in neonates after a complicated delivery within the first month of life. While uncommon, hypercalcemia can be fatal. It is characterized by red-purple plaques in fatty points along with firm subcutaneous nodules. Rarely, SCFN may cause severe hypercalcemia with no visible skin lesion. In this rare case, we report severe infancy hypercalcemia without characteristic skin lesion on first physical examination, unresponsive to hydration, diuretic, prednisolone, and standard dose of pamidronate treatment. As timely diagnosis and treatment is so important, this complication should be kept in mind even in such clinical presentations.

Key words: Hypercalcemia, subcutaneous fat necrosis, pamidronate, infant


 
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How to Cite this Article
Pubmed Style

Dibeklioglu SE, Bas VN, Yalinbas EE, Umay ST. The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion. Sudan J Paed. 2022; 22(1): 98-103. doi:10.24911/SJP.106-1602681630


Web Style

Dibeklioglu SE, Bas VN, Yalinbas EE, Umay ST. The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion. https://www.sudanjp.com/?mno=13577 [Access: August 01, 2022]. doi:10.24911/SJP.106-1602681630


AMA (American Medical Association) Style

Dibeklioglu SE, Bas VN, Yalinbas EE, Umay ST. The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion. Sudan J Paed. 2022; 22(1): 98-103. doi:10.24911/SJP.106-1602681630



Vancouver/ICMJE Style

Dibeklioglu SE, Bas VN, Yalinbas EE, Umay ST. The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion. Sudan J Paed. (2022), [cited August 01, 2022]; 22(1): 98-103. doi:10.24911/SJP.106-1602681630



Harvard Style

Dibeklioglu, S. E., Bas, . V. N., Yalinbas, . E. E. & Umay, . S. T. (2022) The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion. Sudan J Paed, 22 (1), 98-103. doi:10.24911/SJP.106-1602681630



Turabian Style

Dibeklioglu, Saime Ergen, Veysel Nijat Bas, Emine Esin Yalinbas, and Sermin Tok Umay. 2022. The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion. Sudanese Journal of Paediatrics, 22 (1), 98-103. doi:10.24911/SJP.106-1602681630



Chicago Style

Dibeklioglu, Saime Ergen, Veysel Nijat Bas, Emine Esin Yalinbas, and Sermin Tok Umay. "The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion." Sudanese Journal of Paediatrics 22 (2022), 98-103. doi:10.24911/SJP.106-1602681630



MLA (The Modern Language Association) Style

Dibeklioglu, Saime Ergen, Veysel Nijat Bas, Emine Esin Yalinbas, and Sermin Tok Umay. "The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion." Sudanese Journal of Paediatrics 22.1 (2022), 98-103. Print. doi:10.24911/SJP.106-1602681630



APA (American Psychological Association) Style

Dibeklioglu, S. E., Bas, . V. N., Yalinbas, . E. E. & Umay, . S. T. (2022) The cause of severe hypercalcaemia resistant to pamidronate treatment: subcutaneous fat necrosis with no visible skin lesion. Sudanese Journal of Paediatrics, 22 (1), 98-103. doi:10.24911/SJP.106-1602681630





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