Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management

Haydar El Hadi Babikir

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Sudan J Paed. 2010; 10(1): 14-23

Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management

Haydar El Hadi Babikir.

Abstract
Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. In general, malaria is a curable disease if diagnosed and treated promptly and correctly. Severe malaria occurs most often in persons who have no immunity to malaria or whose immunity has decreased. Cerebral malaria (CM) collectively involves the clinical manifestations of Plasmodium falciparum malaria that induce changes in mental status and coma. It is an acute, widespread disease of the brain which is accompanied by fever. The mortality ratio is between 25 - 50%. If a person is not treated, CM is fatal in 24 - 72% hours. This article is meant to review the problem of cerebral malaria in children with respect to clinical features, pathophysiology and management.

Key words: cerebral malaria, children, pathogenesis, PfEMP-1 IFN-y, TNF-a

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Pubmed Style

Haydar El Hadi Babikir. Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management.

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Haydar El Hadi Babikir. Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management. https://sudanjp.com//?mno=105974 [Access: June 22, 2024].

AMA (American Medical Association) Style

Haydar El Hadi Babikir. Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management.

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Haydar El Hadi Babikir. Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management.

Harvard Style

Haydar El Hadi Babikir (2010) Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management.

Turabian Style

Haydar El Hadi Babikir. 2010. Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management.

Chicago Style

Haydar El Hadi Babikir. "Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management."

MLA (The Modern Language Association) Style

Haydar El Hadi Babikir. "Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management."

APA (American Psychological Association) Style

Haydar El Hadi Babikir (2010) Cerebral Malaria in Children: A Review of Pathophysiology. Clinical Manifestations and Management.

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