E-ISSN 1858-8360 | ISSN 0256-4408
 

Case Report 


A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review

Bashir Abdrhman Bashir, Suhair A. Othman, Amel Aziz Malik.

Abstract
Evans syndrome is a condition in which autoimmune-mediated red blood cells and platelet destruction happens consecutively. It may be associated with a reduction in neutrophil count as a result of immune neutropenia. No sex preference is known and it presents in all ages and any ethnic cohort. Generally, this syndrome tends to be chronic and is characterised by remission and exacerbation. We document a case of the immune-mediated disease associated with Epstein-Barr virus infection in an 8-year-old boy from eastern Sudan who presented with both immune thrombocytopenia purpura and autoimmune haemolytic anaemia. Complete blood count and peripheral blood picture revealed features consistent with immune haemolytic anaemia (rouleaux formation and spherocytes) and thrombocytopenia. Direct anti-human globulin test and indirect antihuman globulin test were positive. Evans syndrome is a potentially life-threatening condition due to the concomitant existence with antiplatelet and anti-erythrocyte antibodies distinguished by a positive antiglobulin test and possibly linked to other autoimmune or lymphoproliferative diseases.

Key words: Evans syndrome; Autoimmune haemolytic anaemia; Immune thrombocytopenia; Direct antiglobulin test.


 
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How to Cite this Article
Pubmed Style

Bashir BA, Othman SA, Malik AA. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudan J Paed. 2021; 21(1): 89-94. doi:10.24911/SJP.106-1583095341


Web Style

Bashir BA, Othman SA, Malik AA. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. http://www.sudanjp.com/?mno=90008 [Access: April 09, 2021]. doi:10.24911/SJP.106-1583095341


AMA (American Medical Association) Style

Bashir BA, Othman SA, Malik AA. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudan J Paed. 2021; 21(1): 89-94. doi:10.24911/SJP.106-1583095341



Vancouver/ICMJE Style

Bashir BA, Othman SA, Malik AA. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudan J Paed. (2021), [cited April 09, 2021]; 21(1): 89-94. doi:10.24911/SJP.106-1583095341



Harvard Style

Bashir, B. A., Othman, . S. A. & Malik, . A. A. (2021) A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudan J Paed, 21 (1), 89-94. doi:10.24911/SJP.106-1583095341



Turabian Style

Bashir, Bashir Abdrhman, Suhair A. Othman, and Amel Aziz Malik. 2021. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudanese Journal of Paediatrics, 21 (1), 89-94. doi:10.24911/SJP.106-1583095341



Chicago Style

Bashir, Bashir Abdrhman, Suhair A. Othman, and Amel Aziz Malik. "A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review." Sudanese Journal of Paediatrics 21 (2021), 89-94. doi:10.24911/SJP.106-1583095341



MLA (The Modern Language Association) Style

Bashir, Bashir Abdrhman, Suhair A. Othman, and Amel Aziz Malik. "A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review." Sudanese Journal of Paediatrics 21.1 (2021), 89-94. Print. doi:10.24911/SJP.106-1583095341



APA (American Psychological Association) Style

Bashir, B. A., Othman, . S. A. & Malik, . A. A. (2021) A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudanese Journal of Paediatrics, 21 (1), 89-94. doi:10.24911/SJP.106-1583095341





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