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Online Published: 10 Dec 2024
 


Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis

Naveen Kumar Meel, Rajeeb Adhikari, Preetham Patavardhan, Pruthvi Raj Kandikonda, Pradip Ghimire, Sonal Saran.


Abstract
Osteopetrosis, a hereditary bone disorder, leads to thickening of the bone cortex and narrowing of the medullary canal due to abnormal osteoclast function. Known as Albers-Schönberg disease, it has two forms: autosomal recessive and autosomal dominant. Chronic osteomyelitis, occurring in about 10% of cases, is a common complication characterized by facial swelling, sinus discharge, jaw pain, and fever, often stemming from dental infections. Diagnosis relies on clinical, lab, and radiological assessments. In this case, a 17-year-old male presented with facial swelling persisting for six months and intermittent fever. Contrast-enhanced CT scan revealed lytic-sclerotic lesions in the mandible and maxilla, along with cervical spine sclerosis. Diagnosis of jaw osteomyelitis in Osteopetrosis was confirmed. Management entails tailored antibiotic therapy, surgical debridement, and adjunctive therapies like hyperbaric oxygen. Due to its complexity, achieving a cure is challenging, with recurrent symptoms common. Multidisciplinary care involving orthopedic, infectious disease, and maxillofacial specialists is essential for comprehensive evaluation and management, aiming to improve patient outcomes and quality of life.

Key words: Osteopetrosis, Albers-Schönberg disease, hereditary bone disorder, chronic osteomyelitis


 
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How to Cite this Article
Pubmed Style

Meel NK, Adhikari R, Patavardhan P, Kandikonda PR, Ghimire P, Saran S. Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis. Sudan J Paed. Online First: 10 Dec, 2024. doi:10.24911/SJP.106-1708575202

Web Style

Meel NK, Adhikari R, Patavardhan P, Kandikonda PR, Ghimire P, Saran S. Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis. https://sudanjp.com//?mno=191872 [Access: December 10, 2024]. doi:10.24911/SJP.106-1708575202

AMA (American Medical Association) Style

Meel NK, Adhikari R, Patavardhan P, Kandikonda PR, Ghimire P, Saran S. Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis. Sudan J Paed. Online First: 10 Dec, 2024. doi:10.24911/SJP.106-1708575202


Vancouver/ICMJE Style

Meel NK, Adhikari R, Patavardhan P, Kandikonda PR, Ghimire P, Saran S. Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis. Sudan J Paed, [cited December 10, 2024]; Online First: 10 Dec, 2024. doi:10.24911/SJP.106-1708575202


Harvard Style

Meel, N. K., Adhikari, . R., Patavardhan, . P., Kandikonda, . P. R., Ghimire, . P. & Saran, . S. (2024) Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis. Sudan J Paed, Online First: 10 Dec, 2024. doi:10.24911/SJP.106-1708575202


Turabian Style

Meel, Naveen Kumar, Rajeeb Adhikari, Preetham Patavardhan, Pruthvi Raj Kandikonda, Pradip Ghimire, and Sonal Saran. 2024. Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis. Sudanese Journal of Paediatrics, Online First: 10 Dec, 2024. doi:10.24911/SJP.106-1708575202


Chicago Style

Meel, Naveen Kumar, Rajeeb Adhikari, Preetham Patavardhan, Pruthvi Raj Kandikonda, Pradip Ghimire, and Sonal Saran. "Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis." Sudanese Journal of Paediatrics Online First: 10 Dec, 2024. doi:10.24911/SJP.106-1708575202


MLA (The Modern Language Association) Style

Meel, Naveen Kumar, Rajeeb Adhikari, Preetham Patavardhan, Pruthvi Raj Kandikonda, Pradip Ghimire, and Sonal Saran. "Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis." Sudanese Journal of Paediatrics Online First: 10 Dec, 2024. Web. 10 Dec 2024 doi:10.24911/SJP.106-1708575202


APA (American Psychological Association) Style

Meel, N. K., Adhikari, . R., Patavardhan, . P., Kandikonda, . P. R., Ghimire, . P. & Saran, . S. (2024) Clinico-radiological findings in osteopetrosis with mandibular osteomyelitis. Sudanese Journal of Paediatrics, Online First: 10 Dec, 2024. doi:10.24911/SJP.106-1708575202




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