Pyridoxine in isoniazid-induced psychosis

Renu Yadav; Manish Kumar; Niraj Kumar; Swathi Chacham

doi:10.24911/SJP.106-1584524803

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Online Publishing Date:
03 / 02 / 2023

Sudan J Paed. 2022; 22(2): 190-192

doi: 10.24911/SJP.106-1584524803

Pyridoxine in isoniazid-induced psychosis

Renu Yadav, Manish Kumar, Niraj Kumar, Swathi Chacham.

Abstract
Isoniazid is a first-line drug for the management of tuberculosis. Recent changes in paediatric tuberculosis guidelines have insisted on a higher daily dose of isoniazid. Given the burden of paediatric tuberculosis in developing countries, it is pertinent that paediatricians are well versed with all possible adverse effects associated with isoniazid therapy and not just common ones like hepatotoxicity or peripheral neuropathy. Psychosis is one such rare adverse effect which has a reported incidence of 1%–2%. Here, we report a case of isoniazid-induced psychosis in a 4-year-old girl. The purpose of this report is to sensitise the paediatric healthcare community regarding this rare clinical entity along with highlighting the putative role of pyridoxine supplementation in the management of isoniazidinduced psychosis.

Key words: Tuberculosis, Isoniazid, Psychosis, Pyridoxine

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How to Cite this Article

Pubmed Style

Yadav R, Kumar M, Kumar N, Chacham S. Pyridoxine in isoniazid-induced psychosis. Sudan J Paed. 2022; 22(2): 190-192. doi:10.24911/SJP.106-1584524803

Web Style

Yadav R, Kumar M, Kumar N, Chacham S. Pyridoxine in isoniazid-induced psychosis. https://sudanjp.com//?mno=93370 [Access: June 21, 2024]. doi:10.24911/SJP.106-1584524803

AMA (American Medical Association) Style

Yadav R, Kumar M, Kumar N, Chacham S. Pyridoxine in isoniazid-induced psychosis. Sudan J Paed. 2022; 22(2): 190-192. doi:10.24911/SJP.106-1584524803

Vancouver/ICMJE Style

Yadav R, Kumar M, Kumar N, Chacham S. Pyridoxine in isoniazid-induced psychosis. Sudan J Paed. (2022), [cited June 21, 2024]; 22(2): 190-192. doi:10.24911/SJP.106-1584524803

Harvard Style

Yadav, R., Kumar, . M., Kumar, . N. & Chacham, . S. (2022) Pyridoxine in isoniazid-induced psychosis. Sudan J Paed, 22 (2), 190-192. doi:10.24911/SJP.106-1584524803

Turabian Style

Yadav, Renu, Manish Kumar, Niraj Kumar, and Swathi Chacham. 2022. Pyridoxine in isoniazid-induced psychosis. Sudanese Journal of Paediatrics, 22 (2), 190-192. doi:10.24911/SJP.106-1584524803

Chicago Style

Yadav, Renu, Manish Kumar, Niraj Kumar, and Swathi Chacham. "Pyridoxine in isoniazid-induced psychosis." Sudanese Journal of Paediatrics 22 (2022), 190-192. doi:10.24911/SJP.106-1584524803

MLA (The Modern Language Association) Style

Yadav, Renu, Manish Kumar, Niraj Kumar, and Swathi Chacham. "Pyridoxine in isoniazid-induced psychosis." Sudanese Journal of Paediatrics 22.2 (2022), 190-192. Print. doi:10.24911/SJP.106-1584524803

APA (American Psychological Association) Style

Yadav, R., Kumar, . M., Kumar, . N. & Chacham, . S. (2022) Pyridoxine in isoniazid-induced psychosis. Sudanese Journal of Paediatrics, 22 (2), 190-192. doi:10.24911/SJP.106-1584524803

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