A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review

Bashir Abdrhman Bashir; Suhair A. Othman; Amel Aziz Malik

doi:10.24911/SJP.106-1583095341

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Sudan J Paed. 2021; 21(1): 89-94

doi: 10.24911/SJP.106-1583095341

A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review

Bashir Abdrhman Bashir, Suhair A. Othman, Amel Aziz Malik.

Abstract
Evans syndrome is a condition in which autoimmune-mediated red blood cells and platelet destruction happens consecutively. It may be associated with a reduction in neutrophil count as a result of immune neutropenia. No sex preference is known and it presents in all ages and any ethnic cohort. Generally, this syndrome tends to be chronic and is characterised by remission and exacerbation. We document a case of the immune-mediated disease associated with Epstein-Barr virus infection in an 8-year-old boy from eastern Sudan who presented with both immune thrombocytopenia purpura and autoimmune haemolytic anaemia. Complete blood count and peripheral blood picture revealed features consistent with immune haemolytic anaemia (rouleaux formation and spherocytes) and thrombocytopenia. Direct anti-human globulin test and indirect antihuman globulin test were positive. Evans syndrome is a potentially life-threatening condition due to the concomitant existence with antiplatelet and anti-erythrocyte antibodies distinguished by a positive antiglobulin test and possibly linked to other autoimmune or lymphoproliferative diseases.

Key words: Evans syndrome; Autoimmune haemolytic anaemia; Immune thrombocytopenia; Direct antiglobulin test.

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Pubmed Style

Bashir BA, Othman SA, Malik AA. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudan J Paed. 2021; 21(1): 89-94. doi:10.24911/SJP.106-1583095341

Web Style

Bashir BA, Othman SA, Malik AA. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. https://sudanjp.com//?mno=90008 [Access: June 22, 2024]. doi:10.24911/SJP.106-1583095341

AMA (American Medical Association) Style

Bashir BA, Othman SA, Malik AA. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudan J Paed. 2021; 21(1): 89-94. doi:10.24911/SJP.106-1583095341

Vancouver/ICMJE Style

Bashir BA, Othman SA, Malik AA. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudan J Paed. (2021), [cited June 22, 2024]; 21(1): 89-94. doi:10.24911/SJP.106-1583095341

Harvard Style

Bashir, B. A., Othman, . S. A. & Malik, . A. A. (2021) A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudan J Paed, 21 (1), 89-94. doi:10.24911/SJP.106-1583095341

Turabian Style

Bashir, Bashir Abdrhman, Suhair A. Othman, and Amel Aziz Malik. 2021. A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudanese Journal of Paediatrics, 21 (1), 89-94. doi:10.24911/SJP.106-1583095341

Chicago Style

Bashir, Bashir Abdrhman, Suhair A. Othman, and Amel Aziz Malik. "A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review." Sudanese Journal of Paediatrics 21 (2021), 89-94. doi:10.24911/SJP.106-1583095341

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Bashir, B. A., Othman, . S. A. & Malik, . A. A. (2021) A rare haematological disorder in a Sudanese child: Evans syndrome, case report and literature review. Sudanese Journal of Paediatrics, 21 (1), 89-94. doi:10.24911/SJP.106-1583095341

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