Congenital insensitivity to pain with anhidrosis in Sudanese children.

Suhair A Othman; Amel A Malik

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Sudan J Paed. 2016; 16(2): 80-85

Congenital insensitivity to pain with anhidrosis in Sudanese children.

Suhair A Othman, Amel A Malik.

Abstract
Congenital insensitivity to pain with anhidrosis (CIPA), also called hereditary sensory and autonomic neuropathy type IV (HSAN-IV), is an extremely rare autosomal recessive disease. It is characterized by insensitivity to pain, inability to sweat, episodes of hyperpyrexia, and intellectual disability. These factors render the affected persons to repeatedly injure and traumatise themselves to the degree that they become disabled. No specific treatment to the moment, but it needs multidisciplinary approach, and certain life adaptations and education. Here we report 4 unrelated Sudanese children affected with this rare neurological disorder, to raise the awareness on this rare disease, reflecting its spectrum, and the challenges which patients and their families face, especially when living in a hot country.

Key words: Anhidrosis; Congenital insensitivity to pain; Hereditary sensory and autonomic neuropathy type IV; Hyperpyrexia; Self-mutilation; Vitamin A toxicity

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Pubmed Style

Othman SA, Malik AA. Congenital insensitivity to pain with anhidrosis in Sudanese children.. Sudan J Paed. 2016; 16(2): 80-85.

Web Style

Othman SA, Malik AA. Congenital insensitivity to pain with anhidrosis in Sudanese children.. https://sudanjp.com//?mno=280619 [Access: June 22, 2024].

AMA (American Medical Association) Style

Othman SA, Malik AA. Congenital insensitivity to pain with anhidrosis in Sudanese children.. Sudan J Paed. 2016; 16(2): 80-85.

Vancouver/ICMJE Style

Othman SA, Malik AA. Congenital insensitivity to pain with anhidrosis in Sudanese children.. Sudan J Paed. (2016), [cited June 22, 2024]; 16(2): 80-85.

Harvard Style

Othman, S. A. & Malik, . A. A. (2016) Congenital insensitivity to pain with anhidrosis in Sudanese children.. Sudan J Paed, 16 (2), 80-85.

Turabian Style

Othman, Suhair A, and Amel A Malik. 2016. Congenital insensitivity to pain with anhidrosis in Sudanese children.. Sudanese Journal of Paediatrics, 16 (2), 80-85.

Chicago Style

Othman, Suhair A, and Amel A Malik. "Congenital insensitivity to pain with anhidrosis in Sudanese children.." Sudanese Journal of Paediatrics 16 (2016), 80-85.

MLA (The Modern Language Association) Style

Othman, Suhair A, and Amel A Malik. "Congenital insensitivity to pain with anhidrosis in Sudanese children.." Sudanese Journal of Paediatrics 16.2 (2016), 80-85. Print.

APA (American Psychological Association) Style

Othman, S. A. & Malik, . A. A. (2016) Congenital insensitivity to pain with anhidrosis in Sudanese children.. Sudanese Journal of Paediatrics, 16 (2), 80-85.

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