E-ISSN 1858-8360 | ISSN 0256-4408
 

Short Communication 


Karyotype analysis in children with idiopathic intellectual disability

Hüseyin Çaksen, Hayrettin Okut, Mevlit İkbal.

Abstract
Intellectual disability is a heterogeneous condition, affecting 1-3% of general population. In this study, karyotype analysis was performed in 33 children with idiopathic ID in a hospital with limited laboratory facilities to determine value of karyotype analysis as a first step test in children with idiopathic ID. Thirty-three patients with idiopathic intellectual disability were included in the study. GTL banding karyotype resolution at a standard resolution of 550 bands was performed to determine whether the patients had microdeletion/microduplication by using of conventional karyotype analysis. Of 33 children, seven (21.2%) showed various chromosomal changes. Polymorphisms including 46,XX,1qh+; 46,XX,1qh+,1qh+; 46,X,add(Y),q12; 46,XY,21ps+; and 46,XX,1qh+ were diagnosed in five children. Inversion (46,XY,inv9(p12q13), and inversion and polymorphisms (46,XY,inv9(p12q13),13ps+) were diagnosed in two children, respectively. We think that inv(9)(p12q13) is a benign variant. In conclusion, our findings showed that karyotype analysis was not helpful to determine etiology in children with idiopathic ID because of probably low patient number in our study.

Key words: Idiopathic intellectual disability; Chromosomal analysis; Child


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Hüseyin Çaksen
Articles by Hayrettin Okut
Articles by Mevlit İkbal
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Caksen H, Okut H, İkbal M, . Karyotype analysis in children with idiopathic intellectual disability. Sudan J Paed. 2019; 19(1): 57-59. doi:10.24911/SJP.106-1539963785


Web Style

Caksen H, Okut H, İkbal M, . Karyotype analysis in children with idiopathic intellectual disability. https://sudanjp.com//?mno=13463 [Access: February 06, 2024]. doi:10.24911/SJP.106-1539963785


AMA (American Medical Association) Style

Caksen H, Okut H, İkbal M, . Karyotype analysis in children with idiopathic intellectual disability. Sudan J Paed. 2019; 19(1): 57-59. doi:10.24911/SJP.106-1539963785



Vancouver/ICMJE Style

Caksen H, Okut H, İkbal M, . Karyotype analysis in children with idiopathic intellectual disability. Sudan J Paed. (2019), [cited February 06, 2024]; 19(1): 57-59. doi:10.24911/SJP.106-1539963785



Harvard Style

Caksen, H. ., Okut, H. ., İkbal, M. . & (2019) Karyotype analysis in children with idiopathic intellectual disability. Sudan J Paed, 19 (1), 57-59. doi:10.24911/SJP.106-1539963785



Turabian Style

Caksen, Huseyin , Hayrettin Okut, Mevlit İkbal, and . 2019. Karyotype analysis in children with idiopathic intellectual disability. Sudanese Journal of Paediatrics, 19 (1), 57-59. doi:10.24911/SJP.106-1539963785



Chicago Style

Caksen, Huseyin , Hayrettin Okut, Mevlit İkbal, and . "Karyotype analysis in children with idiopathic intellectual disability." Sudanese Journal of Paediatrics 19 (2019), 57-59. doi:10.24911/SJP.106-1539963785



MLA (The Modern Language Association) Style

Caksen, Huseyin , Hayrettin Okut, Mevlit İkbal, and . "Karyotype analysis in children with idiopathic intellectual disability." Sudanese Journal of Paediatrics 19.1 (2019), 57-59. Print. doi:10.24911/SJP.106-1539963785



APA (American Psychological Association) Style

Caksen, H. ., Okut, H. ., İkbal, M. . & (2019) Karyotype analysis in children with idiopathic intellectual disability. Sudanese Journal of Paediatrics, 19 (1), 57-59. doi:10.24911/SJP.106-1539963785





Most Viewed Articles
Most Accessed Articles

  • Rheumatic heart disease in North Darfur: an alarmingly high burden and control initiative
    Nagwa Salih, Ishag Eisa, Daresalam Ishag, Intisar Ibrahim, Sulafa Ali
    Sudan J Paed. 2018; 18(1): 24-27
    » Abstract » doi: 10.24911/SJP.2018.1.4

  • Feeding growth restricted premature neonates: a challenging perspective
    Siba Prosad Paul, Emily Natasha Kirkham, Katherine Amy Hawton, Paul Anthony Mannix
    Sudan J Paed. 2018; 18(2): 5-14
    » Abstract » doi: 10.24911/SJP.106-1519511375

  • Congenital brain malformations in Sudanese children: an outpatient-based study
    Inaam Noureldyme Mohammed, Soad Abdalaziz Suliman, Maha A Elseed, Ahlam Abdalrhman Hamed, Mohamed Osman Babiker, Shaimaa Osman Taha
    Sudan J Paed. 2018; 18(1): 48-56
    » Abstract » doi: 10.24911/SJP.2018.1.7

  • Evaluation of Science. [eng]
    Adnan Mahmmood Usmani; Sultan Ayoub Meo
    Sudan J Paed. 2011; 11(1): 6-7
    » Abstract

  • Medical education and services in an extreme environment
    Mustafa Abdalla M. Salih, Mohammed Osman Swar
    Sudan J Paed. 2018; 18(1): 2-5
    » Abstract » doi: 10.24911/SJP.2018.1.1

  • Most Downloaded
    Top Downloaded Articles

  • The role of micronutrients in thyroid dysfunction
    Amir Babiker, Afnan Alawi, Mohsen Al Atawi, Ibrahim Al Alwan
    Sudan J Paed. 2020; 20(1): 13-19
    » Abstract » doi: 10.24911/SJP.106-1587138942

  • Why mothers are not exclusively breast feeding their babies till 6 months of age? Knowledge and practices data from two large cities of the Kingdom of Saudi Arabia
    Hafsa Raheel, Shabana Tharkar
    Sudan J Paed. 2018; 18(1): 28-38
    » Abstract » doi: 10.24911/SJP.2018.1.5

  • Relactation in lactation failure and low milk supply
    Anita Mehta, Arvind Kumar Rathi, Komal Prasad Kushwaha, Abhishek Singh
    Sudan J Paed. 2018; 18(1): 39-47
    » Abstract » doi: 10.24911/SJP.2018.1.6

  • Inborn errors of metabolism associated with hyperglycaemic ketoacidosis and diabetes mellitus: narrative review
    Majid Alfadhel, Amir Babiker
    Sudan J Paed. 2018; 18(1): 10-23
    » Abstract » doi: 10.24911/SJP.2018.1.3

  • Neonatal polycythaemia
    Bashir Abdrhman Bashir, Suhair Abdrahim Othman
    Sudan J Paed. 2019; 19(2): 81-83
    » Abstract » doi: 10.24911/SJP.106-1566075225

  • Most Cited Articles
    Most Cited Articles

  • Anti-diabetic medications: How to make a choice?
    Amir Babiker, Mohammed Al Dubayee
    Sudan J Paed. 2017; 17(2): 11-20
    » Abstract » doi: 10.24911/SJP.2017.2.12
    Cited : 8 times [Click to see citing articles]

  • Commitment to the wellbeing of children worldwide. [eng]
    Mustafa Abdalla M Salih; Satti Abdelrahim Satti
    Sudan J Paed. 2011; 11(2): 4-5
    » Abstract
    Cited : 4 times [Click to see citing articles]

  • Pattern of malaria in hospitalized children in Khartoum state
    Hasan Awadalla Hashim, Eltigani Mohamed Ahmed Ali
    Sudan J Paed. 2017; 17(2): 35-41
    » Abstract » doi: 10.24911/SJP.2017.2.4
    Cited : 4 times [Click to see citing articles]

  • The role of micronutrients in thyroid dysfunction
    Amir Babiker, Afnan Alawi, Mohsen Al Atawi, Ibrahim Al Alwan
    Sudan J Paed. 2020; 20(1): 13-19
    » Abstract » doi: 10.24911/SJP.106-1587138942
    Cited : 4 times [Click to see citing articles]

  • Broad beans ( Vicia faba ) and the potential to protect from COVID-19 coronavirus infection
    Mutasim I. Khalil, Mustafa A. Salih, Ali A. Mustafa
    Sudan J Paed. 2020; 20(1): 10-12
    » Abstract » doi: 10.24911/SJP.1061585398078
    Cited : 4 times [Click to see citing articles]